hCOMET session

hCOMET COST-Action session - 19th of May, 2021:

Programme:

09:00 - 09:15 Welcome and introduction

~ Prof. Andrew Collins, University of Oslo, Norway

Topic 1 - DNA damage and repair as predictive biomarkers

09:15 __ T1-1: European cohort studies on predictive biomarkers: Preliminary results on the comet assay

~ Stefano Bonassi, IRCCS San Raffaele Pisana Rome, Italy

09:45 __ T1-2: DNA repair as endpoint in human biomonitoring studies; results from hCOMET and how to move forward

~ Roger Godschalk, Maastricht University, Netherlands

Topic 2 - Standardising the comet assay

10:00 __ T2-1: Using simple physics to understand and control the comet assay

~ Gunnar Brunborg, Norwegian Institute of Public Health, Norway

10:15 __ T2-2: Genome size separation in the comet assay give several opportunities

~ Kristine Bjerve Gutzow, Norwegian Institute of Public Health, Norway

10:30 - 11:00 Coffee break

11:00 __ T2-3: Potassium bromate as positive assay control for the Fpg-modified comet assay

~ Peter Moller, University of Copenhagen, Denmark

11:15 __ T2-4: On the way to a more reliable comet assay; technical aspects and recommendations

~ Amaya Azqueta, University of Navarra, Spain

Topic 3 - Use of blood fractions and different cell types, biobanks

11:30 __ T3-1: Possible use of blood-derived biobank samples for analysis with the comet assay

~ Helga Stopper, University of Würzburg, Germany

11:45 __ T3-2: Comet assay for the evaluation of DNA damage from frozen human whole blood

~ Goran Gajski, Institute for Medical Research and Occupational Health, Croatia

12:00 __ T3-3: The comet assay for human biomonitoring: Effect of cryopreservation on DNA damage in different blood cell preparations

~ Lisa Giovannelli, University of Florence, Italy

12:15 __ T3-4: Use of salivary lymphocytes in exposure assessment

~ Massimo Moretti, University of Perugia, Italy

12:30 __ Open discussion about hCOMET findings